Lexus ES 350
25 MPG The 2025 Lexus ES 350 is EPA-rated at 25 MPG combined (22 city / 32 highway). Over 15,000 miles a year that is about 600 gallons, $1920 a year in fuel, or $0.128 per mile at $3.20/gal.
Across its full 2007–2025 run it averages 24.1 MPG, improving by 3 MPG over 19 model years.
Running cost at different fuel prices and mileages
The figure everyone actually wants, and the one the EPA does not publish — because it depends on a fuel price no agency will commit to.
| Fuel price | Per mile | 10,000 mi/yr | 15,000 mi/yr | 20,000 mi/yr |
|---|---|---|---|---|
| $2.50/gal | $0.100 | $1000 | $1500 | $2000 |
| $3.00/gal | $0.120 | $1200 | $1800 | $2400 |
| $3.20/gal | $0.128 | $1280 | $1920 | $2560 |
| $3.50/gal | $0.140 | $1400 | $2100 | $2800 |
| $4.00/gal | $0.160 | $1600 | $2400 | $3200 |
| $4.50/gal | $0.180 | $1800 | $2700 | $3600 |
| $5.00/gal | $0.200 | $2000 | $3000 | $4000 |
Every model year
| Year | Combined | City | Highway | EPA fuel cost/yr | CO₂ g/mi | Trims |
|---|---|---|---|---|---|---|
| 2025 | 25 MPG | 22 | 32 | $2500 | 347 | 1 |
| 2024 | 26 MPG | 22 | 32 | $2400 | 346 | 1 |
| 2023 | 26 MPG | 22 | 32 | $2400 | 346 | 1 |
| 2022 | 26 MPG | 22 | 32 | $2400 | 344 | 1 |
| 2021 | 26 MPG | 22 | 32 | $2400 | 346 | 1 |
| 2020 | 26 MPG | 22 | 32 | $2400 | 346 | 1 |
| 2019 | 26 MPG | 22 | 33 | $2400 | 343 | 1 |
| 2018 | 24 MPG | 21 | 30 | $2600 | 366 | 1 |
| 2017 | 24 MPG | 21 | 30 | $2600 | 365 | 1 |
| 2016 | 24 MPG | 21 | 31 | $2600 | 363 | 1 |
| 2015 | 24 MPG | 21 | 31 | $2600 | 364 | 1 |
| 2014 | 24 MPG | 21 | 30 | $2600 | 365 | 1 |
| 2013 | 24 MPG | 21 | 31 | $2600 | 365 | 1 |
| 2012 | 22 MPG | 19 | 27 | $2850 | 404 | 1 |
| 2011 | 22 MPG | 19 | 27 | $2850 | 404 | 1 |
| 2010 | 22 MPG | 19 | 27 | $3500 | 404 | 1 |
| 2009 | 22 MPG | 19 | 27 | $3500 | 404 | 1 |
| 2008 | 22 MPG | 19 | 27 | $3500 | 404 | 1 |
| 2007 | 22 MPG | 19 | 27 | $3500 | 404 | 1 |
Where a model year offered several engines or drivetrains, the figure is the average across all EPA-tested trims that year — the trim count is shown so you can see how much averaging is involved.
How it compares in its class
Among the 261 midsize cars models tracked here, the Lexus ES 350 ranks 104 on current figures, against a class average of 27.2 MPG.
Closest more-efficient alternatives in the same class: Ford Fusion FWD (25.3), Audi A6 quattro (25.5), Chrysler 200 (25.7), Alfa Romeo Giulia AWD (26), BMW 528i xDrive (26).
Tailpipe CO₂ is rated at 347 grams per mile, which works out to roughly 5.2 tonnes a year at 15,000 miles.
Questions
What MPG does the Lexus ES 350 get?
The 2025 Lexus ES 350 is rated at 25 MPG combined by the EPA — 22 city and 32 highway. Across all 19 model years in the database it averages 24.1 MPG, ranging from 22 to 26 depending on year and trim.
How much does a Lexus ES 350 cost in fuel per year?
At 25 MPG and 15,000 miles a year, it burns about 600 gallons — roughly $1920 a year with fuel at $3.20 a gallon, or $0.128 per mile. The EPA's own published annual figure for the 2025 model is $2500.
Has the Lexus ES 350 become more efficient over time?
Yes. It has gone from 22 MPG in 2007 to 25 in 2025 — an improvement of 3 MPG, or 14% across 19 model years.
Is the Lexus ES 350 efficient for its class?
It ranks 104 of 261 in the Midsize Cars class on current figures, against a class average of 27.2 MPG. That is 2.2 worse than typical for the class.
EPA test figures from fueleconomy.gov. Cost per mile and annual fuel spend are computed at a reference price of $3.20 per gallon — use your own price. Estimates based on official test figures and average fuel prices. Real-world consumption varies with driving style, load, terrain and maintenance.