Mercedes-Benz AMG C43 4matic
22 MPG The 2026 Mercedes-Benz AMG C43 4matic is EPA-rated at 22 MPG combined (19 city / 27 highway). Over 15,000 miles a year that is about 682 gallons, $2182 a year in fuel, or $0.145 per mile at $3.20/gal.
Across its full 2017–2026 run it averages 22.2 MPG, falling by 1 MPG over 9 model years.
Running cost at different fuel prices and mileages
The figure everyone actually wants, and the one the EPA does not publish — because it depends on a fuel price no agency will commit to.
| Fuel price | Per mile | 10,000 mi/yr | 15,000 mi/yr | 20,000 mi/yr |
|---|---|---|---|---|
| $2.50/gal | $0.114 | $1136 | $1705 | $2273 |
| $3.00/gal | $0.136 | $1364 | $2045 | $2727 |
| $3.20/gal | $0.145 | $1455 | $2182 | $2909 |
| $3.50/gal | $0.159 | $1591 | $2386 | $3182 |
| $4.00/gal | $0.182 | $1818 | $2727 | $3636 |
| $4.50/gal | $0.205 | $2045 | $3068 | $4091 |
| $5.00/gal | $0.227 | $2273 | $3409 | $4545 |
Every model year
| Year | Combined | City | Highway | EPA fuel cost/yr | CO₂ g/mi | Trims |
|---|---|---|---|---|---|---|
| 2026 | 22 MPG | 19 | 27 | $3500 | 405 | 1 |
| 2025 | 22 MPG | 19 | 27 | $3500 | 405 | 1 |
| 2024 | 23 MPG | 20 | 28 | $3350 | 389 | 1 |
| 2023 | 22 MPG | 19 | 26 | $3500 | 403 | 1 |
| 2021 | 21 MPG | 18 | 27 | $3650 | 428 | 1 |
| 2020 | 22 MPG | 19 | 27 | $3500 | 407 | 1 |
| 2019 | 22 MPG | 19 | 27 | $3500 | 407 | 1 |
| 2018 | 23 MPG | 20 | 27 | $3350 | 393 | 1 |
| 2017 | 23 MPG | 20 | 28 | $3350 | 382 | 1 |
Where a model year offered several engines or drivetrains, the figure is the average across all EPA-tested trims that year — the trim count is shown so you can see how much averaging is involved.
How it compares in its class
Among the 227 compact cars models tracked here, the Mercedes-Benz AMG C43 4matic ranks 144 on current figures, against a class average of 26.6 MPG.
Closest more-efficient alternatives in the same class: Cadillac ATS AWD (22.5), Chevrolet Corsica (22.5), Ford Contour (22.5), Mercury Mystique (22.5), Nissan Altima / Stanza (22.5).
Tailpipe CO₂ is rated at 405 grams per mile, which works out to roughly 6.1 tonnes a year at 15,000 miles.
Questions
What MPG does the Mercedes-Benz AMG C43 4matic get?
The 2026 Mercedes-Benz AMG C43 4matic is rated at 22 MPG combined by the EPA — 19 city and 27 highway. Across all 9 model years in the database it averages 22.2 MPG, ranging from 21 to 23 depending on year and trim.
How much does a Mercedes-Benz AMG C43 4matic cost in fuel per year?
At 22 MPG and 15,000 miles a year, it burns about 682 gallons — roughly $2182 a year with fuel at $3.20 a gallon, or $0.145 per mile. The EPA's own published annual figure for the 2026 model is $3500.
Has the Mercedes-Benz AMG C43 4matic become more efficient over time?
No — it has actually gone backwards, from 23 MPG in 2017 to 22 in 2026. That usually reflects the model growing heavier, more powerful, or moving upmarket rather than the engineering getting worse.
Is the Mercedes-Benz AMG C43 4matic efficient for its class?
It ranks 144 of 227 in the Compact Cars class on current figures, against a class average of 26.6 MPG. That is 4.6 worse than typical for the class.
EPA test figures from fueleconomy.gov. Cost per mile and annual fuel spend are computed at a reference price of $3.20 per gallon — use your own price. Estimates based on official test figures and average fuel prices. Real-world consumption varies with driving style, load, terrain and maintenance.