Mercedes-Benz AMG E53 4matic Plus
24 MPG The 2023 Mercedes-Benz AMG E53 4matic Plus is EPA-rated at 24 MPG combined (21 city / 29 highway). Over 15,000 miles a year that is about 625 gallons, $2000 a year in fuel, or $0.133 per mile at $3.20/gal.
Across its full 2019–2023 run it averages 24.2 MPG, essentially flat across 5 model years.
Running cost at different fuel prices and mileages
The figure everyone actually wants, and the one the EPA does not publish — because it depends on a fuel price no agency will commit to.
| Fuel price | Per mile | 10,000 mi/yr | 15,000 mi/yr | 20,000 mi/yr |
|---|---|---|---|---|
| $2.50/gal | $0.104 | $1042 | $1563 | $2083 |
| $3.00/gal | $0.125 | $1250 | $1875 | $2500 |
| $3.20/gal | $0.133 | $1333 | $2000 | $2667 |
| $3.50/gal | $0.146 | $1458 | $2188 | $2917 |
| $4.00/gal | $0.167 | $1667 | $2500 | $3333 |
| $4.50/gal | $0.188 | $1875 | $2813 | $3750 |
| $5.00/gal | $0.208 | $2083 | $3125 | $4167 |
Every model year
| Year | Combined | City | Highway | EPA fuel cost/yr | CO₂ g/mi | Trims |
|---|---|---|---|---|---|---|
| 2023 | 24 MPG | 21 | 29 | $3200 | 364 | 1 |
| 2022 | 24 MPG | 21 | 29 | $3200 | 373 | 1 |
| 2021 | 25 MPG | 22 | 29 | $3100 | 361 | 1 |
| 2020 | 24 MPG | 21 | 28 | $3200 | 370 | 1 |
| 2019 | 24 MPG | 21 | 28 | $3200 | 370 | 1 |
Where a model year offered several engines or drivetrains, the figure is the average across all EPA-tested trims that year — the trim count is shown so you can see how much averaging is involved.
How it compares in its class
Among the 261 midsize cars models tracked here, the Mercedes-Benz AMG E53 4matic Plus ranks 114 on current figures, against a class average of 27.2 MPG.
Closest more-efficient alternatives in the same class: Mercury Milan (24.5), Audi A7 quattro (25), Jaguar XF AWD (25), Lexus ES 350 (25), Lexus ES 350 F Sport (25).
Tailpipe CO₂ is rated at 364 grams per mile, which works out to roughly 5.5 tonnes a year at 15,000 miles.
Questions
What MPG does the Mercedes-Benz AMG E53 4matic Plus get?
The 2023 Mercedes-Benz AMG E53 4matic Plus is rated at 24 MPG combined by the EPA — 21 city and 29 highway. Across all 5 model years in the database it averages 24.2 MPG, ranging from 24 to 25 depending on year and trim.
How much does a Mercedes-Benz AMG E53 4matic Plus cost in fuel per year?
At 24 MPG and 15,000 miles a year, it burns about 625 gallons — roughly $2000 a year with fuel at $3.20 a gallon, or $0.133 per mile. The EPA's own published annual figure for the 2023 model is $3200.
Has the Mercedes-Benz AMG E53 4matic Plus become more efficient over time?
Barely. It sits at 24 MPG today against 24 in 2019 — essentially flat across 5 model years, with efficiency gains offset by weight and power creep.
Is the Mercedes-Benz AMG E53 4matic Plus efficient for its class?
It ranks 114 of 261 in the Midsize Cars class on current figures, against a class average of 27.2 MPG. That is 3.2 worse than typical for the class.
EPA test figures from fueleconomy.gov. Cost per mile and annual fuel spend are computed at a reference price of $3.20 per gallon — use your own price. Estimates based on official test figures and average fuel prices. Real-world consumption varies with driving style, load, terrain and maintenance.